Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye)

Aysel Veyisoğlu; Demet Tatar; Dilara Yılmaz; Hünkar Avni Duyar

doi:10.3153/AR26026

EN

Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye)

Abstract

This study comparatively evaluated the antimicrobial and antioxidant activities of ethanol extracts obtained from the marine macroalgae Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast of the Black Sea (Türkiye). Antimicrobial activity was determined using the disk diffusion method against selected Gram-positive and Gram-negative bacteria as well as yeast and filamentous fungal strains. Antioxidant activity was assessed using the DPPH radical scavenging assay, and IC₅₀ values were calculated. The results demonstrated significant species-dependent differences in biological activity. Corallina officinalis exhibited the strongest antibacterial activity against Bacillus subtilis, Brevibacillus brevis, Listeria monocytogenes, Enterobacter aerogenes, and Salmonella typhimurium, whereas Ulva lactuca showed the greatest inhibitory activity against Staphylococcus aureus, Candida glabrata, and Candida tropicalis. Although Cystoseira barbata displayed moderate antimicrobial activity, it exhibited the highest antioxidant capacity, reaching 60.26% DPPH radical scavenging activity at 1000 µg/mL with the lowest IC₅₀ value (577.8 µg/mL). In contrast, Corallina officinalis failed to achieve 50% radical scavenging activity within the tested concentration range (IC₅₀ >1000 µg/mL). These findings indicate that Black Sea macroalgae represent valuable natural sources of bioactive compounds with promising applications in the pharmaceutical, food, nutraceutical, and biotechnology industries. However, further phytochemical characterization, isolation of active compounds, mechanistic studies, and in vivo investigations are required before their therapeutic and industrial applications can be fully established.

Keywords

Supporting Institution

This study was supported by the TÜBİTAK 2209-A University Students Research Projects.

Project Number

TÜBİTAK 2209-A/1919B012502761

Ethical Statement

The authors declare that this study does not involve experiments with human or animal subjects, and therefore, ethics committee approval is not required.

Thanks

We would like to thank TÜBİTAK for its support

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Details

Primary Language

English

Subjects

Hydrobiology

Journal Section

Research Article

Authors

Aysel Veyisoğlu ^*
0000-0002-1406-5513
Türkiye

Demet Tatar
0000-0002-9317-3263
Türkiye

Dilara Yılmaz
0009-0000-2589-298X
Türkiye

Hünkar Avni Duyar
0000-0002-2560-5407
Türkiye

Early Pub Date

September 13, 2026

Publication Date

-

Submission Date

July 19, 2026

Acceptance Date

September 4, 2026

Published in Issue

Year 2026 Number: Advanced Online Publication

DOI

https://doi.org/10.3153/AR26026

IZ

https://izlik.org/JA55HG32SK

Cite

RIS / Bibtex

APA

Veyisoğlu, A., Tatar, D., Yılmaz, D., & Duyar, H. A. (2026). Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye). Aquatic Research, Advanced Online Publication, 323-334. https://doi.org/10.3153/AR26026

AMA

1.Veyisoğlu A, Tatar D, Yılmaz D, Duyar HA. Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye). Aquat Res. 2026;(Advanced Online Publication):323-334. doi:10.3153/AR26026

Chicago

Veyisoğlu, Aysel, Demet Tatar, Dilara Yılmaz, and Hünkar Avni Duyar. 2026. “Comparative Evaluation of the Antimicrobial and Antioxidant Activities of Cystoseira Barbata, Ulva Lactuca, and Corallina Officinalis Collected from the Sinop Coast (Black Sea, Türkiye)”. Aquatic Research, no. Advanced Online Publication: 323-34. https://doi.org/10.3153/AR26026.

EndNote

Veyisoğlu A, Tatar D, Yılmaz D, Duyar HA (September 1, 2026) Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye). Aquatic Research Advanced Online Publication 323–334.

IEEE

[1]A. Veyisoğlu, D. Tatar, D. Yılmaz, and H. A. Duyar, “Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye)”, Aquat Res, no. Advanced Online Publication, pp. 323–334, Sept. 2026, doi: 10.3153/AR26026.

ISNAD

Veyisoğlu, Aysel - Tatar, Demet - Yılmaz, Dilara - Duyar, Hünkar Avni. “Comparative Evaluation of the Antimicrobial and Antioxidant Activities of Cystoseira Barbata, Ulva Lactuca, and Corallina Officinalis Collected from the Sinop Coast (Black Sea, Türkiye)”. Aquatic Research. Advanced Online Publication (September 1, 2026): 323-334. https://doi.org/10.3153/AR26026.

JAMA

1.Veyisoğlu A, Tatar D, Yılmaz D, Duyar HA. Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye). Aquat Res. 2026;:323–334.

MLA

Veyisoğlu, Aysel, et al. “Comparative Evaluation of the Antimicrobial and Antioxidant Activities of Cystoseira Barbata, Ulva Lactuca, and Corallina Officinalis Collected from the Sinop Coast (Black Sea, Türkiye)”. Aquatic Research, no. Advanced Online Publication, Sept. 2026, pp. 323-34, doi:10.3153/AR26026.

Vancouver

1.Aysel Veyisoğlu, Demet Tatar, Dilara Yılmaz, Hünkar Avni Duyar. Comparative evaluation of the antimicrobial and antioxidant activities of Cystoseira barbata, Ulva lactuca, and Corallina officinalis collected from the Sinop coast (Black Sea, Türkiye). Aquat Res. 2026 Sep. 1;(Advanced Online Publication):323-34. doi:10.3153/AR26026