The role of Eleutherine palmifolia (Dayak Onion) as a natural immunostimulant for enhancing fish disease resistance in aquaculture systems

Adimas Bagus Fahturohman; Bagus Ansani Takwin; Wijayanti Ristyaningrum; Zakyatul Muna; Stella Feska

doi:10.3153/AR26013

EN

The role of Eleutherine palmifolia (Dayak Onion) as a natural immunostimulant for enhancing fish disease resistance in aquaculture systems

Abstract

The global food crisis, driven by population growth, climate change, and natural resource degradation, has intensified the need for efficient, affordable, and environmentally sustainable sources of animal protein. In aquaculture, this demand has accelerated the exploration of alternative feed ingredients and natural additives that enhance immune responses, suppress pathogens, and promote fish growth. Eleutherine palmifolia (Dayak onion), an endemic plant from Kalimantan, has emerged as a promising candidate due to its strong antibacterial activity and safety profile without chemical residues. Using a PRISMA-guided systematic review, this study synthesises current evidence on the phytochemical composition, immunological mechanisms, antibacterial activity, and application potential of E. palmifolia in sustainable aquaculture. The extract exhibits anti-inflammatory effects by modulating pro-inflammatory cytokines, enhancing TNF-α expression while reducing IL-β levels, thereby supporting a balanced immune response without excessive oxidative stress. Both ethanol and aqueous extracts effectively inhibit Escherichia coli, Salmonella typhi, and Vibrio cholerae. The plant’s secondary metabolites, including flavonoids, naphthoquinones, polyphenols, tannins, and saponins, demonstrate broad biological activities that improve fish health, growth, and disease resistance. Overall, E. palmifolia holds strong potential as an immunostimulant, antioxidant, and phytobiotic agent for environmentally friendly aquaculture practices.

Keywords

Ethical Statement

This study does not involve experiments on humans or endangered species. All data were obtained from previously published literature and analyzed following PRISMA guidelines. No ethical approval was required.

Thanks

The authors would like to thank the academic staff and students of Nusa Cendana University for their valuable input during manuscript preparation. Special appreciation is extended to the reviewers for their constructive feedback

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Details

Primary Language

English

Subjects

Fish Pests and Diseases , Aquaculture

Journal Section

Review Article

Authors

Adimas Bagus Fahturohman ^*
0009-0007-2203-4374
Indonesia

Bagus Ansani Takwin
0009-0001-6004-5409
Indonesia

Wijayanti Ristyaningrum
0009-0007-1005-0457
Indonesia

Zakyatul Muna
0009-0000-6006-0759
Indonesia

Stella Feska
0000-0002-5685-0245
Indonesia

Early Pub Date

March 30, 2026

Publication Date

March 30, 2026

Submission Date

December 26, 2025

Acceptance Date

February 10, 2026

Published in Issue

Year 1970 Volume: 9 Number: 2

DOI

https://doi.org/10.3153/AR26013

IZ

https://izlik.org/JA57US54DB

Cite

RIS / Bibtex

APA

Bagus Fahturohman, A., Ansani Takwin, B., Ristyaningrum, W., Muna, Z., & Feska, S. (2026). The role of Eleutherine palmifolia (Dayak Onion) as a natural immunostimulant for enhancing fish disease resistance in aquaculture systems. Aquatic Research, 9(2), 148-165. https://doi.org/10.3153/AR26013

The role of Eleutherine palmifolia (Dayak Onion) as a natural immunostimulant for enhancing fish disease resistance in aquaculture systems

Abstract

Keywords

Öz

Ethical Statement

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Early Pub Date

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite