Araştırma Makalesi
BibTex RIS Kaynak Göster

Interaction of Ti-6Al-7Nb alloy with simulated body fluid; a preliminary biocompatibility investigation

Yıl 2023, Cilt: 4 Sayı: 3, 111 - 117, 30.12.2023

Şura Culfa Sıdıka Mine Toker

https://doi.org/10.51753/flsrt.1294479

Öz

The current study aims to investigate the interaction of Ti-6Al-7Nb with simulated body fluid (SBF) in order to apply a preliminary biocompatibility investigation of this novel biomedical alloy, promising for orthopedic applications. Results of the static immersion tests conducted in SBF at body temperature demonstrated that Ca-P rich structures form on the Ti-6Al-7Nb alloy surfaces and the oxide layer formation-dissolution cycle reaches a stable state during immersion. Ion release levels were mostly below critical values except for the initial Al ion release level, which indicated the need for the presence of a stable protective layer on the alloy surface. The second set of static immersion experiments conducted in densified SBF demonstrated that, such a protective layer can rapidly form by biomimetic coating if followed by a preliminary surface treatment. Overall, Ti-6Al-7Nb alloys layers exhibit promising biocompatibility for orthopedic applications, especially with the presence of a stable protective layer.

Anahtar Kelimeler

Biomedical alloy biomimetic coating ion release simulated body fluid Ti-6Al-7Nb

Kaynakça

  • Badhe, R. V., Akinfosile, O., Bijukumar, D., Barba, M., & Mathew, M. T. (2021). Systemic toxicity eliciting metal ion levels from metallic implants and orthopedic devices - A mini review. Toxicology Letters, 35, 213-224.
  • Bauer, S., Schmuki, P., Von Der Mark, K., & Park, J. (2013). Engineering biocompatible implant surfaces: Part I: Materials and surfaces. Progress in Materials Science, 58(3), 261-326.
  • Behera, A. (2021). Advanced Materials: An Introduction to Modern Materials Science. Springer Nature, 1-701. Bocchetta, P., Chen, L. Y., Tardelli, J. D. C., Reis, A. C. D., Almeraya-Calderón, F., & Leo, P. (2021). Passive layers and corrosion resistance of biomedical Ti-6Al-4V and β-Ti alloys. Coatings, 11(5), 487-59.
  • Cingi, M., & Cimenoglu, H. (2010). Ti-6Al-7Nb alaşımının yorulma davranışı. ITU Journal Series D: Engineering, 9(2), 163-167.
  • Fellah, M., Labaïz, M., Assala, O., Dekhil, L., Taleb, A., Rezag, H., & Iost, A. (2014). Tribological behavior of Ti-6Al-4V and Ti-6Al-7Nb alloys for total hip prosthesis. Advances in Tribology, 2014, 13.
  • Hazwani, M. R. S. N., Lim, L. X., Lockman, Z., & Zuhailawati, H. (2022). Fabrication of titanium-based alloys with bioactive surface oxide layer as biomedical implants: Opportunity and challenges. Transactions of Nonferrous Metals Society of China, 32(1), 1-44.
  • Gurel, S., Nazarahari, A., Canadinç, D., Gerstein, G., Maier, H. J., Çabuk, H., ... & Soykan, M. N. (2022). From corrosion behavior to radiation response: A comprehensive biocompatibility assessment of a CoCrMo medium entropy alloy for utility in orthopedic and dental implants. Intermetallics, 149, 107680.
  • Gedikoglu, M., Kolsal, A., Tutus, H., & Toker, SM. (2021). Current approaches in surface processing of biomedical alloys; Laser processes. Gazi University Journal of Science Part C, 9(3), 413-431.
  • Izmir, M., Tufan, Y., & Ercan, B. (2019). Ti-6Al-7Nb’un simule edilmiş vücut sıvısı ile etkileşimi. Journal of the Faculty of Engineering and Architecture of Gazi University, 34(1), 495-504.
  • Li, Q., Kong, L., Xu, S., Gong, H., Li, Y. (2023). Corrosion resistance and cytocompatibility of Ti-19Zr-11Nb-4Ta shape memory alloy for biomedical applications. Journal of Materials Research and Technology, 26, 2352-2357.
  • Liu, Y., Ning, Y., Yao, Z., & Guo, H. (2013). Hot deformation behavior of Ti-6.0Al-7.0Nb biomedical alloy by using processing map. Journal of Alloys and Compounds, 587, 183-189.
  • Mahyudin, F., Widhiyanto, L., & Hemawan, H. (2016). Biomaterials and Medical Devices. A Perspective from an Emerging Country. (pp. 1-249). Cambridge.
  • Manam, N. S., Harun, W. S. W., Shri, D. N. A., Ghani, S. A. C., Kurniawan, T., Ismail, M. H., & Ibrahim, M. H. I. (2017). Study of corrosion in biocompatible metals for implants: A review. Journal of Alloys and Compounds, 701, 698-715.
  • Ozdemir, H. C., Nazarahari, A., Yilmaz, B., Unal, U., Maier, H. J., Canadinc, D., ... & Yilmaz, R. (2023). Understanding the enhanced corrosion performance of two novel Ti-based biomedical high entropy alloys. Journal of Alloys and Compounds, 956, 170343.
  • Sahin, C., Korkmaz, C., & Uzun, G. (2015). Osseointegration surface porosity and nanotechnology. Journal of Dental Faculty of Atatürk University, 13, 174-181.
  • Sarikayak, A., Koc, E., Kalkan, M., & Toker, S. M. (2021). Biomimetic coating of 316L stainless steel with microdeformation areas on the surface. Journal of Polytechnic, 1-12.
  • Titanium Ti-6Al-7Nb Data, (2022). S+D Metals, www.sd-metals.com /en/s-d-materials/titanium-alloys/ti-6al7nb-astm-f1295/ , Last accessed on February 3, 2023.
  • Toker, S. M., Battal E., Demir, Z., & Cevik, K. E. (2020). Interaction of surface modified 316L stainless steel via microdeformation with simulated body fluid. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 8(4), 2455-2467.
  • Toker, S. M., & Canadinc, D. (2014). Evaluation of the biocompatibility of NiTi dental wires: A comparison of laboratory and clinical conditions. Materials Science and Engineering: C, 40, 142-147.
  • Toker, S. M., Canadinc, D., Maier, H. J., & Birer, O. (2014). Evaluation of passive oxide layer formation- biocompatibility relationship in Niti shape memory alloys: Geometry and body location dependency. Materials Science and Engineering: C, 36, 118-129.
  • Toker, S. M., Gerstein, G., Maier, H. J., & Canadinc, D. (2018). Effects of microstructural mechanisms on the localized oxidation behavior of NiTi shape memory alloys in simulated body fluid. Journal of Materials Science, 53(2), 948-958.
  • Toker, S. M., Sugeman, G., & Frey, E. C. (2019). Effects of surface characteristics on the in vitro biocompatibility response of NiTi shape memory alloys. Journal of Engineering and Science, 7(2), 285-290.
  • Tuten, N., Canadinc, D., Motallebzadeh, A., & Bal, B. (2019). Microstructure and tribological properties of TiTaHfNbZr high entropy alloys coatings deposited on Ti-6Al-4V. Intermetallics, 105, 99-106.
  • Yilmaz, B., Evis, Z., & Guldiken, M. (2014). Biomimetic calcium phosphate coating of titanium alloy. Journal of the Faculty of Engineering and Architecture of Gazi University, 29(1), 105-109.
  • Yilmaz, B., Pazarceviren, A. E., Tezcaner, A., & Evis, Z. (2020). Historical development of simulated body fluids used in biomedical applications. Microchemical Journal, 155(1), 1-49.
  • Wei, G., Tan, M., Attarilar, S., Li, J., Uglov, V. V., Wang, B., Liu, J., Lu, L., Wang, L. (2023). An overview of surface modification, A way toward fabrication of nascent biomedical Ti-6Al-4V alloys. Journal of Materials Research and Technology, 24, 5896-5921.

Yıl 2023, Cilt: 4 Sayı: 3, 111 - 117, 30.12.2023

Şura Culfa Sıdıka Mine Toker

https://doi.org/10.51753/flsrt.1294479

Öz

Kaynakça

  • Badhe, R. V., Akinfosile, O., Bijukumar, D., Barba, M., & Mathew, M. T. (2021). Systemic toxicity eliciting metal ion levels from metallic implants and orthopedic devices - A mini review. Toxicology Letters, 35, 213-224.
  • Bauer, S., Schmuki, P., Von Der Mark, K., & Park, J. (2013). Engineering biocompatible implant surfaces: Part I: Materials and surfaces. Progress in Materials Science, 58(3), 261-326.
  • Behera, A. (2021). Advanced Materials: An Introduction to Modern Materials Science. Springer Nature, 1-701. Bocchetta, P., Chen, L. Y., Tardelli, J. D. C., Reis, A. C. D., Almeraya-Calderón, F., & Leo, P. (2021). Passive layers and corrosion resistance of biomedical Ti-6Al-4V and β-Ti alloys. Coatings, 11(5), 487-59.
  • Cingi, M., & Cimenoglu, H. (2010). Ti-6Al-7Nb alaşımının yorulma davranışı. ITU Journal Series D: Engineering, 9(2), 163-167.
  • Fellah, M., Labaïz, M., Assala, O., Dekhil, L., Taleb, A., Rezag, H., & Iost, A. (2014). Tribological behavior of Ti-6Al-4V and Ti-6Al-7Nb alloys for total hip prosthesis. Advances in Tribology, 2014, 13.
  • Hazwani, M. R. S. N., Lim, L. X., Lockman, Z., & Zuhailawati, H. (2022). Fabrication of titanium-based alloys with bioactive surface oxide layer as biomedical implants: Opportunity and challenges. Transactions of Nonferrous Metals Society of China, 32(1), 1-44.
  • Gurel, S., Nazarahari, A., Canadinç, D., Gerstein, G., Maier, H. J., Çabuk, H., ... & Soykan, M. N. (2022). From corrosion behavior to radiation response: A comprehensive biocompatibility assessment of a CoCrMo medium entropy alloy for utility in orthopedic and dental implants. Intermetallics, 149, 107680.
  • Gedikoglu, M., Kolsal, A., Tutus, H., & Toker, SM. (2021). Current approaches in surface processing of biomedical alloys; Laser processes. Gazi University Journal of Science Part C, 9(3), 413-431.
  • Izmir, M., Tufan, Y., & Ercan, B. (2019). Ti-6Al-7Nb’un simule edilmiş vücut sıvısı ile etkileşimi. Journal of the Faculty of Engineering and Architecture of Gazi University, 34(1), 495-504.
  • Li, Q., Kong, L., Xu, S., Gong, H., Li, Y. (2023). Corrosion resistance and cytocompatibility of Ti-19Zr-11Nb-4Ta shape memory alloy for biomedical applications. Journal of Materials Research and Technology, 26, 2352-2357.
  • Liu, Y., Ning, Y., Yao, Z., & Guo, H. (2013). Hot deformation behavior of Ti-6.0Al-7.0Nb biomedical alloy by using processing map. Journal of Alloys and Compounds, 587, 183-189.
  • Mahyudin, F., Widhiyanto, L., & Hemawan, H. (2016). Biomaterials and Medical Devices. A Perspective from an Emerging Country. (pp. 1-249). Cambridge.
  • Manam, N. S., Harun, W. S. W., Shri, D. N. A., Ghani, S. A. C., Kurniawan, T., Ismail, M. H., & Ibrahim, M. H. I. (2017). Study of corrosion in biocompatible metals for implants: A review. Journal of Alloys and Compounds, 701, 698-715.
  • Ozdemir, H. C., Nazarahari, A., Yilmaz, B., Unal, U., Maier, H. J., Canadinc, D., ... & Yilmaz, R. (2023). Understanding the enhanced corrosion performance of two novel Ti-based biomedical high entropy alloys. Journal of Alloys and Compounds, 956, 170343.
  • Sahin, C., Korkmaz, C., & Uzun, G. (2015). Osseointegration surface porosity and nanotechnology. Journal of Dental Faculty of Atatürk University, 13, 174-181.
  • Sarikayak, A., Koc, E., Kalkan, M., & Toker, S. M. (2021). Biomimetic coating of 316L stainless steel with microdeformation areas on the surface. Journal of Polytechnic, 1-12.
  • Titanium Ti-6Al-7Nb Data, (2022). S+D Metals, www.sd-metals.com /en/s-d-materials/titanium-alloys/ti-6al7nb-astm-f1295/ , Last accessed on February 3, 2023.
  • Toker, S. M., Battal E., Demir, Z., & Cevik, K. E. (2020). Interaction of surface modified 316L stainless steel via microdeformation with simulated body fluid. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 8(4), 2455-2467.
  • Toker, S. M., & Canadinc, D. (2014). Evaluation of the biocompatibility of NiTi dental wires: A comparison of laboratory and clinical conditions. Materials Science and Engineering: C, 40, 142-147.
  • Toker, S. M., Canadinc, D., Maier, H. J., & Birer, O. (2014). Evaluation of passive oxide layer formation- biocompatibility relationship in Niti shape memory alloys: Geometry and body location dependency. Materials Science and Engineering: C, 36, 118-129.
  • Toker, S. M., Gerstein, G., Maier, H. J., & Canadinc, D. (2018). Effects of microstructural mechanisms on the localized oxidation behavior of NiTi shape memory alloys in simulated body fluid. Journal of Materials Science, 53(2), 948-958.
  • Toker, S. M., Sugeman, G., & Frey, E. C. (2019). Effects of surface characteristics on the in vitro biocompatibility response of NiTi shape memory alloys. Journal of Engineering and Science, 7(2), 285-290.
  • Tuten, N., Canadinc, D., Motallebzadeh, A., & Bal, B. (2019). Microstructure and tribological properties of TiTaHfNbZr high entropy alloys coatings deposited on Ti-6Al-4V. Intermetallics, 105, 99-106.
  • Yilmaz, B., Evis, Z., & Guldiken, M. (2014). Biomimetic calcium phosphate coating of titanium alloy. Journal of the Faculty of Engineering and Architecture of Gazi University, 29(1), 105-109.
  • Yilmaz, B., Pazarceviren, A. E., Tezcaner, A., & Evis, Z. (2020). Historical development of simulated body fluids used in biomedical applications. Microchemical Journal, 155(1), 1-49.
  • Wei, G., Tan, M., Attarilar, S., Li, J., Uglov, V. V., Wang, B., Liu, J., Lu, L., Wang, L. (2023). An overview of surface modification, A way toward fabrication of nascent biomedical Ti-6Al-4V alloys. Journal of Materials Research and Technology, 24, 5896-5921.
Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Biyomateryaller
Bölüm Araştırma Makaleleri
Yazarlar

Şura Culfa Bu kişi benim 0000-0002-8559-5634

Sıdıka Mine Toker 0000-0003-0762-242X

Yayımlanma Tarihi 30 Aralık 2023
Gönderilme Tarihi 9 Mayıs 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 4 Sayı: 3

Kaynak Göster

APA Culfa, Ş., & Toker, S. M. (2023). Interaction of Ti-6Al-7Nb alloy with simulated body fluid; a preliminary biocompatibility investigation. Frontiers in Life Sciences and Related Technologies, 4(3), 111-117. https://doi.org/10.51753/flsrt.1294479
 Kapak Resmi İndir

Creative Commons License

Frontiers in Life Sciences and Related Technologies is licensed under a Creative Commons Attribution 4.0 International License.