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Investigation of antioxidant activity of the plant Taraxacum farinosum Hausskn. & Bornm

Year 2020, Volume: 3 Issue: 1, 13 - 19, 26.02.2020

Aynur Sarı Nurten Özsoy Seçil Karahüseyin

Abstract

The genus Taraxacum Wigg. is a member of the family Asteraceae. This genus is represented by about 49 species in Turkey. Taraxacum species are commonly used as a diuretic and for the treatment of various diseases such as dyspepsia, reflux, spleen and liver disorders, and anorexia. Compounds from the group of sesquiterpene lactones, triterpenes, phytosterols, flavonoids, lignans, coumarins, phenolic acids, beta-carboline alkaloids, indole alkaloids, and carotenoids have been reported from Taraxacum species. In this study, ethyl acetate and chloroform fractions of methanol extract obtained from root and aerial parts of Taraxacum farinosum Hausskn. & Bornm., an endemic species to Turkey, were investigated in terms of total phenol compound amounts and antioxidant potentials. The highest total phenolic compounds and antioxidant activity were determined in ethyl acetate fractions.. 

Keywords

Taraxacum farinosum antioxidant activity root aerial parts

References

  • 1. Baytop T. Türkiye’de Bitkilerle Tedavi, 1999. İstanbul: Nobel Tıp Kitabevi.
  • 2. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP assay, Analytical Biochemistry. 1996; 239:70-76.
  • 3. Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity, Food Science and Technology.1995; 28:25-30. 4. Buege JA, Aust SD. (): Microsomal lipid peroxidation, Methods in Enzymology. 1978; 52:302-310.
  • 5. Dai G. Dandelion. In: Wang, Y., Deng, W., Xue, C. (Ed.). Pharmacology and application of Chinese Material Medica. Beijing: People’s Medical Publishing House. 1998: 1181-1186.
  • 6. Duh PD, Tu YY, Yen GC. Antioxidant activity of water extract of Harng Jyur (Chrysanthemum morifolium Ramat), Food Science &Technology. 1999; 32:269-277.
  • 7. Gonzalez-Castejon M, Visioli F, Rodriguez-Casado A. Diverse biological activities of dandelion, Nutrition Reviews. 2012; 70(9): 534-547.
  • 8. Hagymasi K, Blazovics A, Feher J, Lugasi A, Kristo Sz. T, Kery A. The in vitro effect of dandelion’s antioxidants on the microsomal lipid peroxidation, Phytother Res. 2000; 14: 43-4.
  • 9. Hagymasi K, Blazovics A, Lugasi A, Kristo Sz. T, Feher J, Kery A. In vitro antioxidant evaluation of dandelion (Taraxacum officinale WEB.) water extracts, Acta Aliment. 2000; 29:1-7.
  • 10. Hu C. Taraxacum: Phytochemistry and health benefits, Chinese Herbal Medicines. 2018; 10:353-61.
  • 11. Kirschner J, Stepanek J. Clonality as part of the evaluation process in Taraxacum, Folia Geobotanica. 1994; 29(2):265-275.
  • 12. Li C, Dong ZB, Jiang JL, Zhao WY. Determination of cichoric acid, caffeic acid, and chlorogenic acid in Taraxaci Herba by HPLC, Chinese Traditional Herbal Drugs. 2015; 46(23):3577-3580.
  • 13. Martinez M, Poirrier P, Chamy R, Prüfer D, SchulzeGronover C, Jorquera L, Ruiz G. Taraxacum officinale and related species: An ethnoparmacological review and its potential as a commercial medicinal plant, J Ethnopharmacol. 2015; 169:244-62.
  • 14. Nishikimi N, Rao NA, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen, Biochemi and Biophys Res Commun 1972; 46:849-54.
  • 15. Önal S, Timur S, Okutucu B, Zihnioğlu F. Inhibition of alpha glucosidase by aqueous extract of some potent antidiabetic medicinal herbs, Preparative Biochemistry & Biotechnology. 2005; 35:29-36.
  • 16. Özdemir E, Alpınar K. (): An ethnobotanical survey of medicinal plants in western part of central Taurus Mountains: Aladaglar (Nigde-Turkey), J Ethnopharmacol. 2015; 166:53-65.
  • 17. Par A, Javor T. Alternatives in hepatoprotectioncytoprotection-influence on monooxygenase system free radical scavengers, Acta Physiologica Hungarica. 1984; 64:409-423.
  • 18. Rice-Evans CA, Miller NJ, Paganga G. Antioxidant properties of phenolic compounds, Trends in Plant Science. 1997; 2:152-59.
  • 19. Schütz K, Carle R, Schieber A. Taraxacum-A review on its phytochemical and pharmacological profile, J Ethnopharmacol, 2006; 107:313-23.
  • 20. Shi SY, Zhou CX, Xu Y, Tao QF, Bai H, Lu FS, Lin WY, Chen HY, Zheng W, Wang LW, Wu YH, Zeng S, Huang KX, Zhao Y, Li X.K, Qu J. Studies on chemical constituents from herbs of Taraxacum mongolicum, Zhongguo Zhong Yao Za Zhi, 2008; 33(10):1147-57.
  • 21. Slinkard K, Singleton VL. Total phenol analyses: automation and comparison with manual methods, Am J Enol Vitic. 1977; 28: 49-55.
  • 22. Uysal A, Zengin G, Güneş E, Ekşinar Uysal N. Çerçeve kayması ve baz çifti değişimi mutasyonlarına karşı etkili doğal iki Taraxacum türü: Mutajenik, antimutajenik, antioksidan değerlendirme, Marmara Pharmaceutical Journal. 2016; 20:311-319.
  • 23. Van Soest J.L. Taraxacum Wiggers. In: Davis, P.H. (Ed.). Flora of Turkey and the East Aegean Islands Vol.5, Edinburgh: University Press. 1975; 788-812.
  • 24. WHO. Resolution-Promotion and Development of Training and Research in Traditional Medicine. 1978 Report No: 622. http://whqlibdoc.who.int/trs/WHO_ TRS_622.pdf

Taraxacum farinosum Hausskn. & Bornm. bitkisinin antioksidan aktivite yönünden incelenmesi

Year 2020, Volume: 3 Issue: 1, 13 - 19, 26.02.2020

Aynur Sarı Nurten Özsoy Seçil Karahüseyin

Abstract

Taraxacum Wigg. cinsi Asteraceae familyasının bir üyesidir. Bu cins Türkiye’de yaklaşık 49 tür ile temsil edilmektedir. Taraxacum türleri halk arasında diüretik olarak, dispepsi, reflü, dalak ve karaciğer rahatsızlıkları, anoreksiya gibi çeşitli hastalıkların tedavisinde kullanılır. Taraxacum türlerinden seskiterpen laktonlar, triterpenler, fitosteroller, flavonoitler, lignanlar, kumarinler, fenolik asitler, beta-karbolin alkaloitleri, indol alkaloitleri, karotenoidler grubundan bileşikler elde edildiği rapor edilmiştir. Bu çalışmada Türkiye için endemik bir tür olan Taraxacum farinosum Hausskn. & Bornm. bitkisinin kök ve toprak üstü kısımlarından elde edilen metanol ekstrelerinin etil asetat ve kloroform fraksiyonları total fenolik bileşik miktarları ve antioksidan potansiyelleri bakımından incelenmiştir. En yüksek total fenolik bileşik miktarı ve antioksidan aktivitenin etil asetat fraksiyonlarında olduğu saptanmıştır. 

Keywords

Taraxacum farinosum antioksidan aktivite kök toprak üstü

References

  • 1. Baytop T. Türkiye’de Bitkilerle Tedavi, 1999. İstanbul: Nobel Tıp Kitabevi.
  • 2. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP assay, Analytical Biochemistry. 1996; 239:70-76.
  • 3. Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity, Food Science and Technology.1995; 28:25-30. 4. Buege JA, Aust SD. (): Microsomal lipid peroxidation, Methods in Enzymology. 1978; 52:302-310.
  • 5. Dai G. Dandelion. In: Wang, Y., Deng, W., Xue, C. (Ed.). Pharmacology and application of Chinese Material Medica. Beijing: People’s Medical Publishing House. 1998: 1181-1186.
  • 6. Duh PD, Tu YY, Yen GC. Antioxidant activity of water extract of Harng Jyur (Chrysanthemum morifolium Ramat), Food Science &Technology. 1999; 32:269-277.
  • 7. Gonzalez-Castejon M, Visioli F, Rodriguez-Casado A. Diverse biological activities of dandelion, Nutrition Reviews. 2012; 70(9): 534-547.
  • 8. Hagymasi K, Blazovics A, Feher J, Lugasi A, Kristo Sz. T, Kery A. The in vitro effect of dandelion’s antioxidants on the microsomal lipid peroxidation, Phytother Res. 2000; 14: 43-4.
  • 9. Hagymasi K, Blazovics A, Lugasi A, Kristo Sz. T, Feher J, Kery A. In vitro antioxidant evaluation of dandelion (Taraxacum officinale WEB.) water extracts, Acta Aliment. 2000; 29:1-7.
  • 10. Hu C. Taraxacum: Phytochemistry and health benefits, Chinese Herbal Medicines. 2018; 10:353-61.
  • 11. Kirschner J, Stepanek J. Clonality as part of the evaluation process in Taraxacum, Folia Geobotanica. 1994; 29(2):265-275.
  • 12. Li C, Dong ZB, Jiang JL, Zhao WY. Determination of cichoric acid, caffeic acid, and chlorogenic acid in Taraxaci Herba by HPLC, Chinese Traditional Herbal Drugs. 2015; 46(23):3577-3580.
  • 13. Martinez M, Poirrier P, Chamy R, Prüfer D, SchulzeGronover C, Jorquera L, Ruiz G. Taraxacum officinale and related species: An ethnoparmacological review and its potential as a commercial medicinal plant, J Ethnopharmacol. 2015; 169:244-62.
  • 14. Nishikimi N, Rao NA, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen, Biochemi and Biophys Res Commun 1972; 46:849-54.
  • 15. Önal S, Timur S, Okutucu B, Zihnioğlu F. Inhibition of alpha glucosidase by aqueous extract of some potent antidiabetic medicinal herbs, Preparative Biochemistry & Biotechnology. 2005; 35:29-36.
  • 16. Özdemir E, Alpınar K. (): An ethnobotanical survey of medicinal plants in western part of central Taurus Mountains: Aladaglar (Nigde-Turkey), J Ethnopharmacol. 2015; 166:53-65.
  • 17. Par A, Javor T. Alternatives in hepatoprotectioncytoprotection-influence on monooxygenase system free radical scavengers, Acta Physiologica Hungarica. 1984; 64:409-423.
  • 18. Rice-Evans CA, Miller NJ, Paganga G. Antioxidant properties of phenolic compounds, Trends in Plant Science. 1997; 2:152-59.
  • 19. Schütz K, Carle R, Schieber A. Taraxacum-A review on its phytochemical and pharmacological profile, J Ethnopharmacol, 2006; 107:313-23.
  • 20. Shi SY, Zhou CX, Xu Y, Tao QF, Bai H, Lu FS, Lin WY, Chen HY, Zheng W, Wang LW, Wu YH, Zeng S, Huang KX, Zhao Y, Li X.K, Qu J. Studies on chemical constituents from herbs of Taraxacum mongolicum, Zhongguo Zhong Yao Za Zhi, 2008; 33(10):1147-57.
  • 21. Slinkard K, Singleton VL. Total phenol analyses: automation and comparison with manual methods, Am J Enol Vitic. 1977; 28: 49-55.
  • 22. Uysal A, Zengin G, Güneş E, Ekşinar Uysal N. Çerçeve kayması ve baz çifti değişimi mutasyonlarına karşı etkili doğal iki Taraxacum türü: Mutajenik, antimutajenik, antioksidan değerlendirme, Marmara Pharmaceutical Journal. 2016; 20:311-319.
  • 23. Van Soest J.L. Taraxacum Wiggers. In: Davis, P.H. (Ed.). Flora of Turkey and the East Aegean Islands Vol.5, Edinburgh: University Press. 1975; 788-812.
  • 24. WHO. Resolution-Promotion and Development of Training and Research in Traditional Medicine. 1978 Report No: 622. http://whqlibdoc.who.int/trs/WHO_ TRS_622.pdf
There are 23 citations in total.

Details

Primary Language Turkish
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Research Articles
Authors

Aynur Sarı This is me 0000-0001-8116-7053

Nurten Özsoy This is me 0000-0002-2419-9128

Seçil Karahüseyin 0000-0002-3515-2974

Publication Date February 26, 2020
Submission Date January 6, 2020
Published in Issue Year 2020 Volume: 3 Issue: 1

Cite

MLA Sarı, Aynur et al. “Taraxacum Farinosum Hausskn. & Bornm. Bitkisinin Antioksidan Aktivite yönünden Incelenmesi”. Sağlık Bilimlerinde İleri Araştırmalar Dergisi, vol. 3, no. 1, 2020, pp. 13-19.
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