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Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı

Year 2021, Volume: 10 Issue: 2, 591 - 597, 27.07.2021
https://doi.org/10.28948/ngumuh.740817

Abstract

Çevre bilincinin her geçen gün artmasıyla, son yıllarda yeşil teknoloji kavramı daha da önem kazanmıştır. Bu kapsamda, tehlikeli maddelerin üretiminin ve tüketiminin azaltılması, harcanan enerji miktarının indirgenmesi ve yenilenebilir kaynakların kullanımının arttırılması amaçlanmaktadır. Gıda, kimya ve ilaç endüstrisinde yaygın olarak kullanılan geleneksel çözücüler yerine, sağlığa zararı olmayan ve yüksek ekstraksiyon verimine sahip çözücülerin kullanımı önerilmektedir. Yeşil çözücüler, toksik olmayan, geri dönüşümü mümkün olabilen, uçucu olmayan ve sentezi için yüksek maliyet gerektirmeyen çözücülerdir. Su, iyonik sıvılar veya süperkritik akışkanlar en çok kullanılan yeşil çözücülerdendir. Son yıllarda bu çözücülerin yanı sıra, derin ötektik çözücüler bu alanda kendine yer bulmuştur. Derin ötektik çözücülerin fiziksel özellikleri iyonik sıvılara benzer olsa da, kimyasal özellikleri farklıdır. Son yıllarda, derin ötektik çözücüler, gıda materyallerinden biyoaktif bileşiklerin (fenolik bileşik, antosiyanin vb.) ekstraksiyonunda yaygın olarak kullanılmaktadır. Bu çözücüler ile ekstraksiyon veriminde önemli ölçüde artış tespit edilmiştir. Bu derleme, gıdalardan biyoaktif bileşiklerin derin ötektik çözücülerle ekstraksiyonu hakkında çalışmaları irdelemektedir.

References

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  • N. Altunay, A. Elik, and R. Gürkan, Preparation and application of alcohol based deep eutectic solvents for extraction of curcumin in food samples prior toits spectrophotometric determination. Food Chemistry, 2019. https://doi: 10.1016/j.foodchem.2019. 125933.
  • A. R. Mansur, N. E. Song, H. Won Jang, T. G. Lim, M. Yoo, and T. Gyu Nam, Optimizing the ultrasound-assisted deep eutectic solvent extraction of flavonoids in common buckwheat sprouts. Food Chemistry, 2019. https://doi:10.1016/j.foodchem.2019.05. 003.
  • A. Garcia, E. Rodríguez-Juan, G. RodríguezGutiérrez, J. J. Rios, and J. Fernández-Bolaños, Extraction of phenolic compounds from virgin olive oil b deep eutectic solvents (DESs). Food Chemistry, 197, 554–561, 2016. https://doi:10.1016/j.food chem.2015.10.13.
  • X. Peng, M. H. Duan, X. H. Yao, Y. H. Zhang, C. J. Zhao, Y. G. Zu, and Y. J. Fu, Green extraction of five target phenolic acids from Lonicerae japonicae Flos with deep eutectic solvent. Separation and Purification Technology, 157, 249–257, 2016. https://doi.org/10. 1016/j.seppur.2015.10.065.
  • Q. Cui, X. Peng, X. H. Yao, Z. F. Wei, M. Luo, W. Wang, C. J. Zhao, Y. J. Fu, and Y. G. Zu, Deep eutectic solvent-based microwave-assisted extraction of genistin, genistein and apigenin from pigeon pea roots. Separation and Purification Technology, 150, 63–72, 2015. https://doi.org/10. 1016 /j. seppur.2015.06.026.
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  • C. G. González, N. R. Mustafa, E. G. Wilson, R. Verpoorte, and Y. H. Choi, Application of natural deep eutectic solvents for the green extraction of vanillin from vanilla pods. Flavour and Fragrance Journal, 33(1), 91–96, 2017. https://doi.org/10.1002 /ffj.3425.
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Utilization of deep eutectic solvents in the extraction of bioactive compounds from food materials

Year 2021, Volume: 10 Issue: 2, 591 - 597, 27.07.2021
https://doi.org/10.28948/ngumuh.740817

Abstract

As the environmental awareness increases, the concept of green technology has gained more importance in recent years. It aims to reduce the production and consumption of hazardous materials, reduce the amount of energy spent and increase the use of renewable resources. It is recommended to use solvents that have non-toxic and high extraction efficiency instead of traditional solvents that are commonly used in the food, chemical and pharmaceutical industries. Green solvents are non-toxic, recyclable, non-volatile and have minimal cost of synthesis. Water, ionic liquids or supercritical fluids are among the most commonly preferred green solvents. In addition to these solvents, deep eutectic solvents took a part in this field in recent years. Although the physical properties of deep eutectic solvents are similar to ionic liquids, their chemical properties are different. In recent years, deep eutectic solvents have been widely used in the extraction of bioactive compounds (phenolic compound, anthocyanin etc.) from food materials. It has been detected a significant increase in extraction efficiency with these solvents. This article reviews the extraction of bioactive compounds from food materials using deep eutectic solvents.

References

  • P. T. Anastas, and J. C. Warner, Green chemistry: Theory and Practice. Oxford University Press Oxford. 1998.
  • M. Poliakoff, and P. Licence, Green chemistry, Nature, vol. 450(6), 810-812, 2007. https://doi.org/10.1038/ 450810a.
  • Y. Marcus, Deep eutectic solvents. Chapter 1: Introduction. Springer Nature Switzerland AG, ISBN: 9783030006075, 2019.
  • L. S. Torres-Valenzuela, A. Ballesteros-Gómez, and S. Rubio, Green solvents for the extraction of high added-value compounds from agri-food waste. Food Engineering Reviews, 12, 83-100, 2020. https://doi. org/10.1007/s12393-019-09206-y.
  • Y. Marcus, Solvent mixtures. Properties and preferential solvation. M. Dekker, New York, ISBN 9780824708375, 2002.
  • A. Loppinet-Serani, C. Aymonier, and F. Cansell, Current and foreseeable applications of süper- critical water for energy and the environment.Chemistry and Sustainability, Emergy and Materials, 1(6), 486–503, 2008. https://doi:10.1002/cssc.200700167.
  • Y. Marcus, Supercritical water. Chapter 1:Introduction. Wiley, New York, ISBN: 9780470889473, 2012.
  • S. P. M. Ventura, F. A. de Silva, M. V. Quental, D. Mondal, M. G. Freire, and J. A. P. Coutinho, Ionic-liquid mediated extraction and separation processes for bioactive compounds: past, present, and future trends. Chemical Reviews, 117, 6984–7052, 2017. https://doi. org/10.1021/acs.chemrev.6b00550.
  • P. Dominguez de Maria, Ionic liquids, switchable solvents and eutectic mixtures. In: Green solvents. Elsevier, Amsterdam, p. 533, 2017.
  • H. Passos, M. G. Freire, and J. A. P. Coutinho, Ionic liquid solutions as extractive solvents for value-added compounds from biomass. Green Chemistry, 16, 4786–4815, 2014. https://doi.org/10.1039/C4GC00236A.
  • E. L. Smith, A. P. Abbott, and K. S. Ryder, Deep eutectic solvents (DESs) and their applications. Chemical Reviews, 114, 11060–11082, 2014. https:// doi.org/10.1021/cr300162p.
  • D. J. G. P. van Osch, L. F. Zubeir, A. van den Bruinhorst, M. A. A. Rocha, and M. C. Kroon, Hydrophobic deep eutectic solvents as water immiscible extractants. Green Chemistry, 17(9), 4518-4521, 2015. https://doi.org/10.1039/C5GC0 1451D.
  • B. D. Ribeiro, C. Florindo, L. C. Iff, M. A. Z. Coelho, and I. M. Marrucho, Menthol-based eutectic mixtures: hydrophobic low viscosity solvents. ACS Sustainable Chemistry & Engineering, 3(10), 2469-2477, 2015. https://doi. org/10.1021/acssuschemeng.5b00532.
  • Z. Maugeri, and P. Dominguez de Maria, Novel choline-chloride-based Deep eutectic solvents with renewable hydrogen bond donors: levulinic acid and sugar-based polyols. RSC Advances, 2(2), 421-425, 2012. https://doi.org/10.1039/C1RA00630D.
  • C. Florindo, F. S. Oliveira, L. P. N. Rebelo, A. M. Fernandes, and I. M. Marrucho, Insights into the synthesis and properties of deep eutectic solvents based on cholinium chloride and carboxylic acids. ACS Sustainable Chemistry&Engineering, 2,2416–2425, 2014. https://doi.org/10.1021/sc500439w.
  • G. Garcia, M. Atilhan, and S. Aparicio, An approach for the rationalization of melting temperature for deep eutectic solvents from DFT. Chemical Physics Letters, 634, 151–155, 2015. https://doi.org/10.1016/j.cplett. 2015.06.017.
  • A. P. Abbott, G. Capper, D. L. Davies, R. K. Rasheed, and V. Tambyrajah, Novel solvent properties of choline chloride/urea mixtures. Chemical Communications, 1, 70–71, 2003. https://doi.org/10.1039/B210714G.
  • A. P. Abbott, P. M. Cullis, M. J. Gibson, R. C. Harris, and E. Raven, Extraction of glycerol from biodiesel into a eutectic based ionic liquid. Green Chemistry, 9, 868–872, 2007. https://doi.org/10. 1039/B702833D.
  • L. F. Zubeir, M. H. M. Lacroix, and M. C. Kroon, Low transition temperature mixtures as innovative and sustainable CO2 capture solvents. The Journal of Physical Chemistry B, 118, 14429–14441, 2014. https://doi.org/10.1021/jp5089004.
  • G. Garcia, S. Aparicio, R. Ullah, and M. Atilhan, Deep eutectic solvents: physicochemical properties and gas separation applications. Energy Fuels, 29, 2616-2644, 2015. doi.org/10.1021/ef5028873.
  • J. Dai, and R. J. Mumper, Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Molecules, 15(10), 7313–7352, 2010. https://doi:10. 3390/molecules15107313.
  • M. S. Jesus, L. F. Ballesteros, R. N. Pereira, Z. Genisheva, A. S. Carvalho, C. Pereira-Wilson, J. A. Teixeira, and L. Domingues, Ohmic heating polyphenolic extracts from vine pruning residue with enhanced biological activity. Food Chemistry, 2020, https://doi:10.1016/j.foodchem.2020.126298.
  • I. Ignat, I. Volf, and V. I. Popa, A critical review of methods for characterization of polyphenolic compounds in fruits and vegetables. Food Chemistry, 126(4), 1821–1835, 2011. https://doi.org/10.1016/j. foodchem.2010.12.026.
  • L. Duan, L. L. Dou, L. Guo, P. Li, and E. H. Liu, Comprehensive evaluation of deep eutectic solvents in extraction of bioactive natural products. ACS Sustainable Chemistry & Engineering, 4(4), 2405–2411, 2016. https://doi.org/10.1021/acssuschemeng. 6b00091.
  • Z. Meng, Z. Jing, D. Hongxia, G. Yuanyuan, and Z. Longshan, Green and efficient extraction of four bioactive flavonoids from Pollen Typhae by ultrasound-assisted deep eutectic solvents extraction. Journal of Pharmaceutical and Biomedical Analysis, 161, 246-253, 2018. https://doi:10.1016/j.jpba.2018. 08.048.
  • M. H. Zainal-Abidin, M. Hayyan, A. Hayyan, and N. S. Jayakumar, New horizons in the extraction of bioactive compounds using deep eutectic solvents: A review. Analytica Chimica Acta, 979, 1–23, 2017. https://doi .org/10.1016/j.aca.2017.05.012.
  • M. C. Cvjetko-Bubalo, N. Ćurko, M. Tomašević, K.Kovačević Ganić, and I. Radojčić Redovniković, Green extraction of grape skin phenolics by using deep eutectic solvents. Food Chemistry, 200, 159–166, 2016.doi.org/10.1016/j.foodchem.2016.01.040.
  • N. Altunay, A. Elik, and R. Gürkan, Preparation and application of alcohol based deep eutectic solvents for extraction of curcumin in food samples prior toits spectrophotometric determination. Food Chemistry, 2019. https://doi: 10.1016/j.foodchem.2019. 125933.
  • A. R. Mansur, N. E. Song, H. Won Jang, T. G. Lim, M. Yoo, and T. Gyu Nam, Optimizing the ultrasound-assisted deep eutectic solvent extraction of flavonoids in common buckwheat sprouts. Food Chemistry, 2019. https://doi:10.1016/j.foodchem.2019.05. 003.
  • A. Garcia, E. Rodríguez-Juan, G. RodríguezGutiérrez, J. J. Rios, and J. Fernández-Bolaños, Extraction of phenolic compounds from virgin olive oil b deep eutectic solvents (DESs). Food Chemistry, 197, 554–561, 2016. https://doi:10.1016/j.food chem.2015.10.13.
  • X. Peng, M. H. Duan, X. H. Yao, Y. H. Zhang, C. J. Zhao, Y. G. Zu, and Y. J. Fu, Green extraction of five target phenolic acids from Lonicerae japonicae Flos with deep eutectic solvent. Separation and Purification Technology, 157, 249–257, 2016. https://doi.org/10. 1016/j.seppur.2015.10.065.
  • Q. Cui, X. Peng, X. H. Yao, Z. F. Wei, M. Luo, W. Wang, C. J. Zhao, Y. J. Fu, and Y. G. Zu, Deep eutectic solvent-based microwave-assisted extraction of genistin, genistein and apigenin from pigeon pea roots. Separation and Purification Technology, 150, 63–72, 2015. https://doi.org/10. 1016 /j. seppur.2015.06.026.
  • B. Xia, D. Yan, Y. Bai, J. Xie, Y. Cao, D. Liao, and L. Lin, Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents. Analytical Methods, 7(21), 9354–9364, 2015. https://doi.org/10. 1039/C5AY02035B.
  • Y. Huang, F. Feng, J. Jiang, Y. Qiao, T. Wu, J. Voglmeir, and Z. G. Chen, Green and efficient extraction of rutin from Tartary buckwheat hull by using natural deep eutectic solvents. Food Chemistry, 221, 1400–1405, 2017. https://doi.org/10.1016/j. foodchem.2016.11.013.
  • E. Bağda, H. Altundağ, and M. Soylak, Highly simple deep eutectic solvent extraction of manganese in vegetable samples prior to ıts ICP-OES analysis. Biological Trace Element Research, 179(2), 334–339, 2017. https://doi.org/10.1007/ s12011-017-0967-5.
  • C. G. González, N. R. Mustafa, E. G. Wilson, R. Verpoorte, and Y. H. Choi, Application of natural deep eutectic solvents for the green extraction of vanillin from vanilla pods. Flavour and Fragrance Journal, 33(1), 91–96, 2017. https://doi.org/10.1002 /ffj.3425.
  • M. W. Nam, J. Zhao, M. S. Lee, J. H. Jeong, and J. Lee, Enhanced extraction of bioactive naturalproducts using tailor-made deep eutectic solvents: application to flavonoid extraction from Flos sophorae. Green Chemistry, 17(3), 1718–1727, 2015. https://doi.org/10. 1039/C4GC01556H.
  • E. Kurtulbaş, A. G. Pekel, M. Bilgin, D. P. Makris, and S. Şahin, Citric acid-based deep eutectic solvent for the anthocyanin recovery from Hibiscus sabdariffa through microwave-assisted extraction. Biomass Conversion and Biorefinery, 2020. https://doi:10.1007/s13399-020-00606-3.
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There are 47 citations in total.

Details

Primary Language Turkish
Subjects Food Engineering
Journal Section Food Engineering
Authors

Naciye Kutlu Kantar 0000-0002-4075-8823

Merve Sılanur Yılmaz 0000-0002-3184-1780

Asli İşci Yakan 0000-0002-8319-0414

Özge Şakıyan Demirkol 0000-0002-0778-8211

Publication Date July 27, 2021
Submission Date May 22, 2020
Acceptance Date January 7, 2021
Published in Issue Year 2021 Volume: 10 Issue: 2

Cite

APA Kutlu Kantar, N., Yılmaz, M. S., İşci Yakan, A., Şakıyan Demirkol, Ö. (2021). Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı. Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi, 10(2), 591-597. https://doi.org/10.28948/ngumuh.740817
AMA Kutlu Kantar N, Yılmaz MS, İşci Yakan A, Şakıyan Demirkol Ö. Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı. NOHU J. Eng. Sci. July 2021;10(2):591-597. doi:10.28948/ngumuh.740817
Chicago Kutlu Kantar, Naciye, Merve Sılanur Yılmaz, Asli İşci Yakan, and Özge Şakıyan Demirkol. “Gıdalardan Biyoaktif bileşiklerin Ekstraksiyonunda Derin ötektik çözücülerin kullanımı”. Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi 10, no. 2 (July 2021): 591-97. https://doi.org/10.28948/ngumuh.740817.
EndNote Kutlu Kantar N, Yılmaz MS, İşci Yakan A, Şakıyan Demirkol Ö (July 1, 2021) Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı. Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi 10 2 591–597.
IEEE N. Kutlu Kantar, M. S. Yılmaz, A. İşci Yakan, and Ö. Şakıyan Demirkol, “Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı”, NOHU J. Eng. Sci., vol. 10, no. 2, pp. 591–597, 2021, doi: 10.28948/ngumuh.740817.
ISNAD Kutlu Kantar, Naciye et al. “Gıdalardan Biyoaktif bileşiklerin Ekstraksiyonunda Derin ötektik çözücülerin kullanımı”. Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi 10/2 (July 2021), 591-597. https://doi.org/10.28948/ngumuh.740817.
JAMA Kutlu Kantar N, Yılmaz MS, İşci Yakan A, Şakıyan Demirkol Ö. Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı. NOHU J. Eng. Sci. 2021;10:591–597.
MLA Kutlu Kantar, Naciye et al. “Gıdalardan Biyoaktif bileşiklerin Ekstraksiyonunda Derin ötektik çözücülerin kullanımı”. Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi, vol. 10, no. 2, 2021, pp. 591-7, doi:10.28948/ngumuh.740817.
Vancouver Kutlu Kantar N, Yılmaz MS, İşci Yakan A, Şakıyan Demirkol Ö. Gıdalardan biyoaktif bileşiklerin ekstraksiyonunda derin ötektik çözücülerin kullanımı. NOHU J. Eng. Sci. 2021;10(2):591-7.

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