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Year 2020, Volume: 3 Issue: 3, 103 - 111, 30.09.2020

Furkan Ayaz Deniz Ayas Nahit Soner Börekçi

Abstract

Supporting Institution

Mersin Üniversitesi

Project Number

2017-2-AP2-2353

References

  • Ayas D., Ağılkaya G. S., KoskerA.R., Durmus M., Ucar Y., et al.,2018a. The Chemical Composition of the Lionfish (Pterois miles, Bennett 1828), the New Invasive Species of the Mediterranean.NESciences, 3(2), 103-115.
  • Ayas D. Ağılkaya G. S., Yağlıoğlu D., 2018b.New record of the red lionfish, Pteroisvolitans (Linnaeus, 1758), in the Northeastern Mediterranean Sea Düzce University Journal of Science & Technology, 6, 871-877.
  • BadilloRB, Banner W, Morris Jr JA, Schaefer SE. A Case Study of Lionish Sting-Induced Paralysis. Aquaculture, Aquarium, Conservation & Legislation-International. Journal of the Bioflux Society (AACLBioflux) 2012; 5.
  • Bariche M., Torres M., Azzurro E., 2013.The presence of the invasive Lionfish Pterois miles in the Mediterranean Sea.Mediterr Mar Sci., 14, 4-292.
  • Bogdanoff A. K., Akins J. L., Morris Jr. J. A., 2013. Invasive Lionfish in the Marketplace: Challenges and Opportunities. P. 140-147. In: 2013 GCFI Lionfish Workgroup Proceedings of the 66th Gulf and Caribbean Fisheries Institute 4 – 8 November 2013. Corpus Christi, Texas, USA.
  • Chaplin D. D., 2010. Overview of the immune response. The Journal of allergy and clinical immunology, 125 (2), 3-23.
  • Chen, L., Deng, H., Cui, H., Fang, J., Zuo, Z., Deng, J., et al.,2017.Inflammatory responses and inflammation-associated diseases in organs. Oncotarget, 9(6), 7204–7218.
  • Crocetta F., Agius D., Balistreri P., Bariche M., Bayhan Y., et al. 2015. A. New Mediterranean Biodiversity Records (October 2015). Mediterr Mar Sci, 16, 682-702.
  • CôtéI.M., Green S.J., Hixon M.A., 2013. Predatory fish invaders: Insights from Indo-Pacific lionfish in the western Atlantic and Caribbean. BiolConserv, 164, 50-61.
  • Fricke, R., 1999. Fishes of the Mascarene Islands (Réunion, Mauritius, Rodriguez): an annotated checklist, with descriptions of new species. Koeltz Scientific Books, Koenigstein, Theses Zoologicae, 31, 759 pp.
  • Galil B.S., Boero F., Campbell M.L., Carlton J.T., Cook E.et al., 2015. ‘Double trouble’: the expansion of the Suez Canal and marine bioinvasions in the Mediterranean Sea. Biol Invasions., 17, 6-973.
  • Golani, D. &Sonin, O., 1992. New records of the Red Sea fishes, Pterois miles (Scorpaenidae) and Pteragoguspelycus (Labridae) from the eastern Mediterranean Sea. Ichthyological Research, 39(2), 167-169. Gökoğlu M., Teker S., Julian D., 2017. “Westward Extension of the Lionfish Pteroisvolitans Linnaeus, 1758 along the Mediterranean Coast of Turkey,” Natural and Engineering Sciences, 2 (2), 67-72.
  • Green S, Akins J., Maljkovic A., CôtéI.M., GoldstienS.J., 2012. Invasive lionfish drive Atlantic coral reef fish declines. PLoS ONE, 7.
  • Gurlek M., Erguden D., Dogdu S.A., Uyan A., Turan C., 2016. “First record red lionfish, Pteroisvolitans (Linnaeus, 1785) in the Mediterranean Sea,” Natural and Engineering Sciences, 1(3), 27-32.
  • Hall-Spencer J.M. and Allen, R., 2015. The Impact of Ocean Acidification on ‘Nuisance’ Species. Research and Reports in Biodiversity Studies 4, 33–46.
  • Iglésias P.S., Frotté L., 2015. Alien marine fishes in Cyprus: update and new records. Aquat Invasions., 10, 38-425.
  • Kapakos, G., Bouallegue, A., Daou, G. B., &Srivastava, A. K., 2010.Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle Cells. Current cardiology reviews, 6(4), 247-254.
  • Kletou D., Hall-Spencer M. J., Kleitou P., 2016. A lionfish (Pterois miles) invasion has begun in the Mediterranean Sea. Marine Biodiversity Records., 9, 46.
  • Kuiter, R.H., Tonozuka, T., 2001.Pictorial guide to Indonesian reef fishes.Part1.Eels- Snappers, Muraenidae - Lutjanidae.Zoonetics, Australia, 302pp.
  • Marshall, J. S., Warrington, R., Watson, W., Kim, H. L., 2018. An introduction to immunology and immunopathology. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 14(2), 49.
  • McCullough A. R., 2002. Four-year review of sildenafil citrate. Reviews in urology, 4 (3), 26-38.
  • Morris, Jr., James A., Akins, J. L., Barse, A., Cerino, D., Freshwater, D. W., Green, S. J, Muñoz, R. C., Paris, C., Whitfield, P. E., 2009. Biology and ecology of the invasive lionfishes, Pterois miles and Pteroisvolitans. Proceedings of the Gulf and Caribbean Fisheries Institute, 61, pp. 409-414.
  • Mouchbahani-Constance S, Lesperance LS, Petitjean H, Davidova A, Macpherson A, et al., 2018. Lionfish venom elicits pain predominantly through the activation of nonpeptidergicnociceptors. Pain.,159(11), 2255-2266.
  • Oray I., Sınay E., SaadetKarakulak F., Yıldız T., 2015. An expected marine alien fish caught at the coast of Northern Cyprus: Pterois miles (Bennett, 1828). J ApplIchthyol., 31, 5-733.
  • SchultR.F., Acquisto N.M., Stair C.K., Wiegand T.J., 2017.A Case of Lionfish Envenomation Presenting to an Inland Emergency Department.Case Rep Emerg Med. 2017, 589-563.
  • Schultz, Eric T., 1986. Pteroisvolitans and Pteroismiles: Two Valid Species. Copeia, vol. 1986, no. 3, pp. 686–690.
  • Sommer, C., Schneider, W., Poutiers, J.M., 1996.The living marine resources of Somalia.FAO species identification field guide for fishery purposes. FAO, Rome, 376 pp.
  • Turan C., Ergüden D., Gürlek M., Yağlıoğlu D., Uyan A., et al., 2014. First record of the Indo-Pacific lionfish Pterois miles (Bennett, 1828) (Osteichthyes: Scorpaenidae) for the Turkish marine waters. J Black Sea/MediterrEnviron., 20, 63-158.
  • Turan C, Öztürk B., 2015. First record of the lionfish Pterois miles from the Aegean Sea. J Black Sea/MediterrEnviron., 21, 8-33.
  • Turvey, S. E., &Broide, D. H.,2010.Innate immunity. The Journal of allergy and clinical immunology, 125(2), 24-32.
  • Wright, J.M., 1988.Seasonal and spatial differences in the fish assemblage of the non-estuarine Sulaibikhat Bay, Kuwait. Marine Biology, 100, 13-20.
  • Yağlıoğlu D., Ayas D., 2016.New occurrence data of four alien fishes (Pisodonophissemicinctus, Pterois miles, Scarusghobban and Parupeneusforsskali) from the North Eastern Mediterranean (Yeşilovacık Bay, Turkey).Biharean Biologist, 10 (2), 150-152.
  • ZenetosA., Ballesteros E., Verlaque M., 2012. “Alien species in the Mediterranean Sea by 2012. A contribution to the application of European Union’s Marine Strategy Framework Directive (MSFD)”, Part 2., Introduction trends and pathways., Mediterranean Marine Science, 13,328–352.

Inflammatory and Erectile Dysfunction (Impotence) Treating Potential of Lionfish Venom

Year 2020, Volume: 3 Issue: 3, 103 - 111, 30.09.2020

Furkan Ayaz Deniz Ayas Nahit Soner Börekçi

Abstract

In this study, we are presenting the inflammatory and aphrodisiac potential of lionfish venom. Based on a case at the east Mediterranean coast of Turkey, our group made observations, certain blood as well as physiological tests to interpret the effect of the venom on the victim. The patient’s blood amounted to an immune response that had an inflammatory character rather than an allergic reaction based on the changes in the white blood cell content. Moreover, the patient had signs of muscle tissue injury as well as arrhythmia. The venom had erectile function increasing activity on the victim who was in line with the previously reported effect of lionfish venom at the intracellular level that also overlaps with the activity of Sildenafil. Our study suggests potential erectile dysfunction (impotence) treatment applications of the lionfish venom and is, to our knowledge, the first study to report and interpret such a potential of the venom.

Keywords

Lionfish Lionfish venom Erectile Dysfunction Impotence Inflammation Muscle Injury

Project Number

2017-2-AP2-2353

References

  • Ayas D., Ağılkaya G. S., KoskerA.R., Durmus M., Ucar Y., et al.,2018a. The Chemical Composition of the Lionfish (Pterois miles, Bennett 1828), the New Invasive Species of the Mediterranean.NESciences, 3(2), 103-115.
  • Ayas D. Ağılkaya G. S., Yağlıoğlu D., 2018b.New record of the red lionfish, Pteroisvolitans (Linnaeus, 1758), in the Northeastern Mediterranean Sea Düzce University Journal of Science & Technology, 6, 871-877.
  • BadilloRB, Banner W, Morris Jr JA, Schaefer SE. A Case Study of Lionish Sting-Induced Paralysis. Aquaculture, Aquarium, Conservation & Legislation-International. Journal of the Bioflux Society (AACLBioflux) 2012; 5.
  • Bariche M., Torres M., Azzurro E., 2013.The presence of the invasive Lionfish Pterois miles in the Mediterranean Sea.Mediterr Mar Sci., 14, 4-292.
  • Bogdanoff A. K., Akins J. L., Morris Jr. J. A., 2013. Invasive Lionfish in the Marketplace: Challenges and Opportunities. P. 140-147. In: 2013 GCFI Lionfish Workgroup Proceedings of the 66th Gulf and Caribbean Fisheries Institute 4 – 8 November 2013. Corpus Christi, Texas, USA.
  • Chaplin D. D., 2010. Overview of the immune response. The Journal of allergy and clinical immunology, 125 (2), 3-23.
  • Chen, L., Deng, H., Cui, H., Fang, J., Zuo, Z., Deng, J., et al.,2017.Inflammatory responses and inflammation-associated diseases in organs. Oncotarget, 9(6), 7204–7218.
  • Crocetta F., Agius D., Balistreri P., Bariche M., Bayhan Y., et al. 2015. A. New Mediterranean Biodiversity Records (October 2015). Mediterr Mar Sci, 16, 682-702.
  • CôtéI.M., Green S.J., Hixon M.A., 2013. Predatory fish invaders: Insights from Indo-Pacific lionfish in the western Atlantic and Caribbean. BiolConserv, 164, 50-61.
  • Fricke, R., 1999. Fishes of the Mascarene Islands (Réunion, Mauritius, Rodriguez): an annotated checklist, with descriptions of new species. Koeltz Scientific Books, Koenigstein, Theses Zoologicae, 31, 759 pp.
  • Galil B.S., Boero F., Campbell M.L., Carlton J.T., Cook E.et al., 2015. ‘Double trouble’: the expansion of the Suez Canal and marine bioinvasions in the Mediterranean Sea. Biol Invasions., 17, 6-973.
  • Golani, D. &Sonin, O., 1992. New records of the Red Sea fishes, Pterois miles (Scorpaenidae) and Pteragoguspelycus (Labridae) from the eastern Mediterranean Sea. Ichthyological Research, 39(2), 167-169. Gökoğlu M., Teker S., Julian D., 2017. “Westward Extension of the Lionfish Pteroisvolitans Linnaeus, 1758 along the Mediterranean Coast of Turkey,” Natural and Engineering Sciences, 2 (2), 67-72.
  • Green S, Akins J., Maljkovic A., CôtéI.M., GoldstienS.J., 2012. Invasive lionfish drive Atlantic coral reef fish declines. PLoS ONE, 7.
  • Gurlek M., Erguden D., Dogdu S.A., Uyan A., Turan C., 2016. “First record red lionfish, Pteroisvolitans (Linnaeus, 1785) in the Mediterranean Sea,” Natural and Engineering Sciences, 1(3), 27-32.
  • Hall-Spencer J.M. and Allen, R., 2015. The Impact of Ocean Acidification on ‘Nuisance’ Species. Research and Reports in Biodiversity Studies 4, 33–46.
  • Iglésias P.S., Frotté L., 2015. Alien marine fishes in Cyprus: update and new records. Aquat Invasions., 10, 38-425.
  • Kapakos, G., Bouallegue, A., Daou, G. B., &Srivastava, A. K., 2010.Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle Cells. Current cardiology reviews, 6(4), 247-254.
  • Kletou D., Hall-Spencer M. J., Kleitou P., 2016. A lionfish (Pterois miles) invasion has begun in the Mediterranean Sea. Marine Biodiversity Records., 9, 46.
  • Kuiter, R.H., Tonozuka, T., 2001.Pictorial guide to Indonesian reef fishes.Part1.Eels- Snappers, Muraenidae - Lutjanidae.Zoonetics, Australia, 302pp.
  • Marshall, J. S., Warrington, R., Watson, W., Kim, H. L., 2018. An introduction to immunology and immunopathology. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 14(2), 49.
  • McCullough A. R., 2002. Four-year review of sildenafil citrate. Reviews in urology, 4 (3), 26-38.
  • Morris, Jr., James A., Akins, J. L., Barse, A., Cerino, D., Freshwater, D. W., Green, S. J, Muñoz, R. C., Paris, C., Whitfield, P. E., 2009. Biology and ecology of the invasive lionfishes, Pterois miles and Pteroisvolitans. Proceedings of the Gulf and Caribbean Fisheries Institute, 61, pp. 409-414.
  • Mouchbahani-Constance S, Lesperance LS, Petitjean H, Davidova A, Macpherson A, et al., 2018. Lionfish venom elicits pain predominantly through the activation of nonpeptidergicnociceptors. Pain.,159(11), 2255-2266.
  • Oray I., Sınay E., SaadetKarakulak F., Yıldız T., 2015. An expected marine alien fish caught at the coast of Northern Cyprus: Pterois miles (Bennett, 1828). J ApplIchthyol., 31, 5-733.
  • SchultR.F., Acquisto N.M., Stair C.K., Wiegand T.J., 2017.A Case of Lionfish Envenomation Presenting to an Inland Emergency Department.Case Rep Emerg Med. 2017, 589-563.
  • Schultz, Eric T., 1986. Pteroisvolitans and Pteroismiles: Two Valid Species. Copeia, vol. 1986, no. 3, pp. 686–690.
  • Sommer, C., Schneider, W., Poutiers, J.M., 1996.The living marine resources of Somalia.FAO species identification field guide for fishery purposes. FAO, Rome, 376 pp.
  • Turan C., Ergüden D., Gürlek M., Yağlıoğlu D., Uyan A., et al., 2014. First record of the Indo-Pacific lionfish Pterois miles (Bennett, 1828) (Osteichthyes: Scorpaenidae) for the Turkish marine waters. J Black Sea/MediterrEnviron., 20, 63-158.
  • Turan C, Öztürk B., 2015. First record of the lionfish Pterois miles from the Aegean Sea. J Black Sea/MediterrEnviron., 21, 8-33.
  • Turvey, S. E., &Broide, D. H.,2010.Innate immunity. The Journal of allergy and clinical immunology, 125(2), 24-32.
  • Wright, J.M., 1988.Seasonal and spatial differences in the fish assemblage of the non-estuarine Sulaibikhat Bay, Kuwait. Marine Biology, 100, 13-20.
  • Yağlıoğlu D., Ayas D., 2016.New occurrence data of four alien fishes (Pisodonophissemicinctus, Pterois miles, Scarusghobban and Parupeneusforsskali) from the North Eastern Mediterranean (Yeşilovacık Bay, Turkey).Biharean Biologist, 10 (2), 150-152.
  • ZenetosA., Ballesteros E., Verlaque M., 2012. “Alien species in the Mediterranean Sea by 2012. A contribution to the application of European Union’s Marine Strategy Framework Directive (MSFD)”, Part 2., Introduction trends and pathways., Mediterranean Marine Science, 13,328–352.
There are 33 citations in total.

Details

Primary Language English
Subjects Hydrobiology
Journal Section Research Articles
Authors

Furkan Ayaz

Deniz Ayas

Nahit Soner Börekçi

Project Number 2017-2-AP2-2353
Publication Date September 30, 2020
Submission Date July 30, 2020
Published in Issue Year 2020 Volume: 3 Issue: 3

Cite

APA Ayaz, F., Ayas, D., & Börekçi, N. S. (2020). Inflammatory and Erectile Dysfunction (Impotence) Treating Potential of Lionfish Venom. Mediterranean Fisheries and Aquaculture Research, 3(3), 103-111. https://doi.org//medfar.v3i56990.775865

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