Research Article
BibTex RIS Cite

Synergistic antibacterial evaluation of Coriandri aetheroleum and linalool with standard antibiotics

Year 2023, Volume: 10 Issue: 3, 323 - 331, 27.08.2023

Gözde Öztürk Gamze Göger Fatih Demirci Betül Demirci

https://doi.org/10.21448/ijsm.1140803

Abstract

Within this work, it was aimed to investigate the in vitro antibacterial properties of the Pharma grade coriander (Coriandrum sativum L.) essential oil, and its combinations. The chemical composition of the essential oil was confirmed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analyses, simultaneously. Furthermore, the potential antibacterial activity of both the essential oil, and (+)-linalool with standard compounds chloramphenicol, and ciprofloxacin were evaluated using an in vitro microdilution assay against a panel of selected pathogens, namely Acinetobacter baumannii, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. Initially, the minimum inhibitory concentrations (MIC) were determined, the essential oil as well as (+)-linalool and the standard antibiotics were combined for the synergistic antibacterial activity potential, where the combination activities were expressed as fractional inhibitory concentration index values (Σ FIC). The Coriander oil was relatively more effective against B. cereus, P. aeruginosa, E. coli, A. baumannii (2500 µg/mL) compared to S. aureus (5000 µg/mL), respectively. (+)- Linalool was found as effective as the essential oil (2500-5000 µg/mL). Coriander oil and antibiotic combinations showed synergistic effects against B. cereus (∑FIC= 0.375), E. coli (∑FIC= 0.078) and S. aureus (∑FIC= 0.375). Combination with (+)-linalool, and antibiotics showed synergistic effects against B. cereus (∑FIC= 0.375), E. coli (∑FIC= 0.093), as well as against S. aureus (∑FIC= 0.375), respectively. To the best of our knowledge, this is the first time of the antimicrobial combination study of linalool, coriander oil, chloramphenicol, and ciprofloxacin. The initial findings of this work suggest further natural product and drug combination evaluations.

Keywords

Coriander Apiaceae Linalool in vitro antibacterial activity synergy

Supporting Institution

Anadolu University-Tübitak

Project Number

BAP (1404S106, 1301S005)-113S250

Thanks

This work was presented at the ISPSA 2015 - Inaugural Symposium of the Phytochemical Society of Asia 2015, Tokushima, Japan. Financial support was by Anadolu University Scientific Research Projects (BAP 1404S106 - 1301S005) and the Tübitak Project (113S250) infrastructure.

References

  • Alves, S., Duarte, A., Sousa, S, Domingues, F.C. (2016). Study of the major essential oil compounds of Coriandrum sativum against Acinetobacter baumannii and the effect of linalool on adhesion, biofilms and quorum sensing. Biofouling, 32(2), 155–165. https://doi.org/10.1080/08927014.2015.1133810
  • Asgarpanah, J., & Kazemivash, N. (2012). Pharmacology and medicinal properties of Coriandrum sativum L. African Journal of Pharmacy and Pharmacology., 6(31), 2340-2345. https://doi.org/10.5897/AJPP12.901
  • Bajpai, M., Mishra, A., & Prakash, D. (2005). Antioxidant and free radical scavenging activities of some leafy vegetables. International Journal of Food Sciences and Nutrition, 56, 473–481. https://doi.org/10.1080/09637480500524299
  • Bakis, Y., Babac, M.T., & Uslu, E. (2011). Updates and improvements of Turkish plants data service (TÜBİVES), In: 6th International Symposium on IEEE, Health Informatics and Bioinformatics (HIBIT), pp. 136-140.
  • Bazargani, M.M., & Rohloff, J. (2015). Antibiofilm activity of essential oils and plant extracts against Staphylococcus aureus and Escherichia coli biofilm. Food Control, 61, 156-164. https://doi.org/10.1016/j.foodcont.2015.09.036
  • Beyzi, E., Güneş, A., & Gürbüz, B. (2017). Effects of humic acid treatments of yield, morphological characteristics and essential oil components of Coriander (Coriandrum sativum L.). Research Journal of Soil Biology, 9(1), 1-8. https://doi.org/10.3923/rjsb.2017
  • Clinical and Laboratory Standards Institute (CLSI) (2006). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, CLSI M7-A7, Clinical and Laboratory Standards Institute. Pennsylvania.
  • Council of Europe (2014). European Pharmacopoeia. 8.0. Council of Europe. Strasbourg, 1220-1222.
  • Ceylan, A. (1997). Tıbbi bitkiler II (Medicinal Plants). Ege University Faculty of Agriculture Press, İzmir, pp. 406.
  • Delaquis, P.J., Stanich, K., Girard, B., & Mazza, G. (2002). Antimicrobial activity of individual and mixed fractions of Dill, Cilantro, Coriander and Eucalyptus essential oils. International Journal of Food Microbiology, 74, 101–109.
  • Demirci, F., Bayramiç, P., Göger, G., Demirci, B., & Baser, K.H.C. (2015). Characterization and antimicrobial evaluation of the essential oil of Pinus pinea L. from Turkey. Natural Voletiles and Essential Oils, 2(2), 39-44.
  • Demirci, F., Güven, K., Demirci, B., Dadandı, M.Y., & Baser, K.H.C. (2008). Antibacterial activity of two Phlomis essential oils against food pathogens. Food Control, 19(12), 1159-1164.
  • Duarte, A., Ferreira, S., Silva, F., & Domingues, F.C.F. (2012). Synergistic activity of coriander oil and conventional antibiotics against Acinetobacter baumannii. Phytomedicine, 19(3-4), 236-238. https://doi.org/10.1016/j.phymed.2011.11.010
  • Ebrahimi, S.N., Hadian, J., & Ranjbar, H. (2010). Essential oil compositions of different accessions of Coriandrum sativum L. from Iran. Natural Product Research, 24(14), 1287–1294. https://doi.org/10.1080/14786410903132316
  • Gallagher, A.M., Flatt, P.R., Duffy, G., & Abdel-Wahab, Y.H.A. (2003). The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr Res., 23, 413–424. https://doi.org/10.1016/S0271-5317(02)00533-X
  • Hornok, L. (1992). The cultivation of medicinal plants, In: Cultivation and Processing of Medicinal Plants. Hornok, L. (ed.), John Wiley and Sons: Budapest, pp. 131-136.
  • Joulain, D., & König, W.A. (1998). The Atlas of Spectra Data of Sesquiterpene Hydrocarbons.
  • Koenig, W.A., Joulain, D., Hochmuth, D.H. (2004). Terpenoids and Related Constituents of Essential Oils, Library of MassFinder 4.
  • Kon, K.V., & Rai, M.K. (2013). Combining essential oils with antibiotics and other antimicrobial agents to overcome multidrug-resistant bacteria, In: Kon, K.V., Rai M.K. (editors), Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components, Academic Press, USA, pp. 149-164.
  • Kubo, I., Fujita, K.I., Kubo, A., Nihei, K.I., & Ogura, T. (2004). Antibacterial activity of Coriander volatile compounds against Salmonella choleraesuis. Journal of Agricultural and Food Chemistry, 52, 3329–3332. https://doi.org/10.1021/jf0354186
  • Mazumder, J., Kumria, R., & Pathak, D. (2014). Evaluation of synergistic antimicrobial activity and antioxidant activity of blend of essential oil contains Fennel, Coriander, Ajowan and Caraway. IOSR Journal of Pharmacy and Biological Sciences, 9(1), 87-94. https://doi.org/10.9790/3008-09148794
  • McLafferty, F.W., & Stauffer, D.B. (1989). The Wiley/NBS Registry of Mass Spectral Data. J. Wiley and Sons.
  • Özek, T., Tabanca, N., Demirci, F., Wedge, D.E., & Başer, K.H.C. (2010). Enantiomeric distribution of some linalool containing essential oils and their biological activities. Records of Natural Products, 4(4), 180-192.
  • Ramadan, M.F., Kroh, L.W., & Mörsel, J.T. (2003). Radical scavenging activity of Black Cumin (Nigella sativa L.), Coriander (Coriandrum sativum L.), and Niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions. Journal of Agricultural and Food Chemistry, 51, 6961–6969. https://doi.org/10.1021/jf0346713
  • Scazzocchio, F., Garzoli, S., Conti, C., Leone, C., Renaioli, C., Pepi, F., & Angiolella, L. (2015). Properties and limits of some essential oils: chemical characterisation, antimicrobial activity, interaction with antibiotics and cytotoxicity. Natural Product Research, 30 (17), 1909-1918. https://doi.org/10.1080/14786419.2015.1086346
  • Silva, F., Ferreira, S., Queiroz, J.A., & Domingues, F.C. (2011). Coriander (Coriandrum sativum L.) essential oil: its antibacterial activity and mode of action evaluated by flow cytometry. Journal of Medical Microbiology, 60, 1479 1486. https://doi.org/10.1099/jmm.0.034157-0
  • Singh, G., Kapoor, I.P.S., Pandey, S.K., Singh, U.K., & Singh, R.K. (2002). Studies on essential oils: Part 10; antibacterial activity of volatile oils of some spices. Phytotherapy Research, 16(7), 680–682. https://doi.org/10.1002/ptr.951
  • Soares, B.V., Morais, S.M., Fontenelle, R.O., Queiroz, V.A., Vila-Nova, N.S., Pereira, C.S., Brito, E.S., Neto, M.S.A., Brito, E.H.S., Cavalcante, C.S.P., Castelo-Branco, D.S.C.M., & Rocha, M.F.G. (2012). Antifungal activity, toxicity and chemical composition of the essential oil of Coriandrum sativum L. fruits. Molecules, 17, 8439-8448. https://doi.org/10.3390/molecules17078439.
  • Stanojevic, D., Comic, L., Stefanovic, O., & Solujic-Sukdolak, S. (2010). In vitro synergistic antibacterial activity of Salvia officinalis L. and some preservatives. Archives of Biological Sciences, 62(1), 175-183. https://doi.org/10.2298/ABS1001175P
  • Toroğlu, S. (2011). In vitro antimicrobial activity and synergistic/antagonistic effect of interactions between antibiotics and some spice essential oils. Journal of Environmental Biology, 32(1), 23-29.
  • Van Vuuren, S.F., Suliman, S., & Viljoen, A.M. (2009). The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. Letters in Applied Microbiology, 48(4), 440-446. https://doi.org/10.1111/j.1472-765X.2008.02548.x

Synergistic antibacterial evaluation of Coriandri aetheroleum and linalool with standard antibiotics

Year 2023, Volume: 10 Issue: 3, 323 - 331, 27.08.2023

Gözde Öztürk Gamze Göger Fatih Demirci Betül Demirci

https://doi.org/10.21448/ijsm.1140803

Abstract

Within this work, it was aimed to investigate the in vitro antibacterial properties of the Pharma grade coriander (Coriandrum sativum L.) essential oil, and its combinations. The chemical composition of the essential oil was confirmed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analyses, simultaneously. Furthermore, the potential antibacterial activity of both the essential oil, and (+)-linalool with standard compounds chloramphenicol, and ciprofloxacin were evaluated using an in vitro microdilution assay against a panel of selected pathogens, namely Acinetobacter baumannii, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. Initially, the minimum inhibitory concentrations (MIC) were determined, the essential oil as well as (+)-linalool and the standard antibiotics were combined for the synergistic antibacterial activity potential, where the combination activities were expressed as fractional inhibitory concentration index values (Σ FIC). The Coriander oil was relatively more effective against B. cereus, P. aeruginosa, E. coli, A. baumannii (2500 µg/mL) compared to S. aureus (5000 µg/mL), respectively. (+)- Linalool was found as effective as the essential oil (2500-5000 µg/mL). Coriander oil and antibiotic combinations showed synergistic effects against B. cereus (∑FIC= 0.375), E. coli (∑FIC= 0.078) and S. aureus (∑FIC= 0.375). Combination with (+)-linalool, and antibiotics showed synergistic effects against B. cereus (∑FIC= 0.375), E. coli (∑FIC= 0.093), as well as against S. aureus (∑FIC= 0.375), respectively. To the best of our knowledge, this is the first time of the antimicrobial combination study of linalool, coriander oil, chloramphenicol, and ciprofloxacin. The initial findings of this work suggest further natural product and drug combination evaluations.

Keywords

Coriander Apiaceae Linalool in vitro antibacterial activity synergy

Project Number

BAP (1404S106, 1301S005)-113S250

References

  • Alves, S., Duarte, A., Sousa, S, Domingues, F.C. (2016). Study of the major essential oil compounds of Coriandrum sativum against Acinetobacter baumannii and the effect of linalool on adhesion, biofilms and quorum sensing. Biofouling, 32(2), 155–165. https://doi.org/10.1080/08927014.2015.1133810
  • Asgarpanah, J., & Kazemivash, N. (2012). Pharmacology and medicinal properties of Coriandrum sativum L. African Journal of Pharmacy and Pharmacology., 6(31), 2340-2345. https://doi.org/10.5897/AJPP12.901
  • Bajpai, M., Mishra, A., & Prakash, D. (2005). Antioxidant and free radical scavenging activities of some leafy vegetables. International Journal of Food Sciences and Nutrition, 56, 473–481. https://doi.org/10.1080/09637480500524299
  • Bakis, Y., Babac, M.T., & Uslu, E. (2011). Updates and improvements of Turkish plants data service (TÜBİVES), In: 6th International Symposium on IEEE, Health Informatics and Bioinformatics (HIBIT), pp. 136-140.
  • Bazargani, M.M., & Rohloff, J. (2015). Antibiofilm activity of essential oils and plant extracts against Staphylococcus aureus and Escherichia coli biofilm. Food Control, 61, 156-164. https://doi.org/10.1016/j.foodcont.2015.09.036
  • Beyzi, E., Güneş, A., & Gürbüz, B. (2017). Effects of humic acid treatments of yield, morphological characteristics and essential oil components of Coriander (Coriandrum sativum L.). Research Journal of Soil Biology, 9(1), 1-8. https://doi.org/10.3923/rjsb.2017
  • Clinical and Laboratory Standards Institute (CLSI) (2006). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, CLSI M7-A7, Clinical and Laboratory Standards Institute. Pennsylvania.
  • Council of Europe (2014). European Pharmacopoeia. 8.0. Council of Europe. Strasbourg, 1220-1222.
  • Ceylan, A. (1997). Tıbbi bitkiler II (Medicinal Plants). Ege University Faculty of Agriculture Press, İzmir, pp. 406.
  • Delaquis, P.J., Stanich, K., Girard, B., & Mazza, G. (2002). Antimicrobial activity of individual and mixed fractions of Dill, Cilantro, Coriander and Eucalyptus essential oils. International Journal of Food Microbiology, 74, 101–109.
  • Demirci, F., Bayramiç, P., Göger, G., Demirci, B., & Baser, K.H.C. (2015). Characterization and antimicrobial evaluation of the essential oil of Pinus pinea L. from Turkey. Natural Voletiles and Essential Oils, 2(2), 39-44.
  • Demirci, F., Güven, K., Demirci, B., Dadandı, M.Y., & Baser, K.H.C. (2008). Antibacterial activity of two Phlomis essential oils against food pathogens. Food Control, 19(12), 1159-1164.
  • Duarte, A., Ferreira, S., Silva, F., & Domingues, F.C.F. (2012). Synergistic activity of coriander oil and conventional antibiotics against Acinetobacter baumannii. Phytomedicine, 19(3-4), 236-238. https://doi.org/10.1016/j.phymed.2011.11.010
  • Ebrahimi, S.N., Hadian, J., & Ranjbar, H. (2010). Essential oil compositions of different accessions of Coriandrum sativum L. from Iran. Natural Product Research, 24(14), 1287–1294. https://doi.org/10.1080/14786410903132316
  • Gallagher, A.M., Flatt, P.R., Duffy, G., & Abdel-Wahab, Y.H.A. (2003). The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr Res., 23, 413–424. https://doi.org/10.1016/S0271-5317(02)00533-X
  • Hornok, L. (1992). The cultivation of medicinal plants, In: Cultivation and Processing of Medicinal Plants. Hornok, L. (ed.), John Wiley and Sons: Budapest, pp. 131-136.
  • Joulain, D., & König, W.A. (1998). The Atlas of Spectra Data of Sesquiterpene Hydrocarbons.
  • Koenig, W.A., Joulain, D., Hochmuth, D.H. (2004). Terpenoids and Related Constituents of Essential Oils, Library of MassFinder 4.
  • Kon, K.V., & Rai, M.K. (2013). Combining essential oils with antibiotics and other antimicrobial agents to overcome multidrug-resistant bacteria, In: Kon, K.V., Rai M.K. (editors), Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components, Academic Press, USA, pp. 149-164.
  • Kubo, I., Fujita, K.I., Kubo, A., Nihei, K.I., & Ogura, T. (2004). Antibacterial activity of Coriander volatile compounds against Salmonella choleraesuis. Journal of Agricultural and Food Chemistry, 52, 3329–3332. https://doi.org/10.1021/jf0354186
  • Mazumder, J., Kumria, R., & Pathak, D. (2014). Evaluation of synergistic antimicrobial activity and antioxidant activity of blend of essential oil contains Fennel, Coriander, Ajowan and Caraway. IOSR Journal of Pharmacy and Biological Sciences, 9(1), 87-94. https://doi.org/10.9790/3008-09148794
  • McLafferty, F.W., & Stauffer, D.B. (1989). The Wiley/NBS Registry of Mass Spectral Data. J. Wiley and Sons.
  • Özek, T., Tabanca, N., Demirci, F., Wedge, D.E., & Başer, K.H.C. (2010). Enantiomeric distribution of some linalool containing essential oils and their biological activities. Records of Natural Products, 4(4), 180-192.
  • Ramadan, M.F., Kroh, L.W., & Mörsel, J.T. (2003). Radical scavenging activity of Black Cumin (Nigella sativa L.), Coriander (Coriandrum sativum L.), and Niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions. Journal of Agricultural and Food Chemistry, 51, 6961–6969. https://doi.org/10.1021/jf0346713
  • Scazzocchio, F., Garzoli, S., Conti, C., Leone, C., Renaioli, C., Pepi, F., & Angiolella, L. (2015). Properties and limits of some essential oils: chemical characterisation, antimicrobial activity, interaction with antibiotics and cytotoxicity. Natural Product Research, 30 (17), 1909-1918. https://doi.org/10.1080/14786419.2015.1086346
  • Silva, F., Ferreira, S., Queiroz, J.A., & Domingues, F.C. (2011). Coriander (Coriandrum sativum L.) essential oil: its antibacterial activity and mode of action evaluated by flow cytometry. Journal of Medical Microbiology, 60, 1479 1486. https://doi.org/10.1099/jmm.0.034157-0
  • Singh, G., Kapoor, I.P.S., Pandey, S.K., Singh, U.K., & Singh, R.K. (2002). Studies on essential oils: Part 10; antibacterial activity of volatile oils of some spices. Phytotherapy Research, 16(7), 680–682. https://doi.org/10.1002/ptr.951
  • Soares, B.V., Morais, S.M., Fontenelle, R.O., Queiroz, V.A., Vila-Nova, N.S., Pereira, C.S., Brito, E.S., Neto, M.S.A., Brito, E.H.S., Cavalcante, C.S.P., Castelo-Branco, D.S.C.M., & Rocha, M.F.G. (2012). Antifungal activity, toxicity and chemical composition of the essential oil of Coriandrum sativum L. fruits. Molecules, 17, 8439-8448. https://doi.org/10.3390/molecules17078439.
  • Stanojevic, D., Comic, L., Stefanovic, O., & Solujic-Sukdolak, S. (2010). In vitro synergistic antibacterial activity of Salvia officinalis L. and some preservatives. Archives of Biological Sciences, 62(1), 175-183. https://doi.org/10.2298/ABS1001175P
  • Toroğlu, S. (2011). In vitro antimicrobial activity and synergistic/antagonistic effect of interactions between antibiotics and some spice essential oils. Journal of Environmental Biology, 32(1), 23-29.
  • Van Vuuren, S.F., Suliman, S., & Viljoen, A.M. (2009). The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. Letters in Applied Microbiology, 48(4), 440-446. https://doi.org/10.1111/j.1472-765X.2008.02548.x
There are 31 citations in total.

Details

Primary Language English
Subjects Plant Biochemistry, Pharmacology and Pharmaceutical Sciences
Journal Section Articles
Authors

Gözde Öztürk 0000-0002-3998-8859

Gamze Göger 0000-0003-2978-5385

Fatih Demirci 0000-0003-1497-3017

Betül Demirci 0000-0003-2343-746X

Project Number BAP (1404S106, 1301S005)-113S250
Early Pub Date July 31, 2023
Publication Date August 27, 2023
Submission Date July 5, 2022
Published in Issue Year 2023 Volume: 10 Issue: 3

Cite

APA Öztürk, G., Göger, G., Demirci, F., Demirci, B. (2023). Synergistic antibacterial evaluation of Coriandri aetheroleum and linalool with standard antibiotics. International Journal of Secondary Metabolite, 10(3), 323-331. https://doi.org/10.21448/ijsm.1140803
International Journal of Secondary Metabolite

e-ISSN: 2148-6905